Diabetic Eye Disease

Diabetes is the number one cause of new blindness in the United States for people under the age of 65. When one thinks of diabetes, one usually thinks about the body's ability to control sugar. Although this is certainly a part of the disease, diabetes is primarily a disease that affects blood vessels and circulation. Diabetes has many different effects on the eye. Cataracts, glaucoma and retinal disease can all be brought on by diabetes.

A cataract is the progressive clouding of the lens inside the eye. Cataracts are usually associated with aging, but diabetes can make cataracts develop sooner than they would otherwise. There are different types of cataracts. One particular type that is associated with diabetes is called a posterior subcapsular cataract. This type of cataract tends to occur in younger people and will progress much more rapidly that the typical type of age-related cataract.

Glaucoma is the disease where pressure builds up inside the eye and causes permanent nerve damage. People with diabetes are much more likely to develop glaucoma than people without diabetes. There is actually a genetic link between diabetes and glaucoma. When diabetic eye disease gets to advanced stages, an unusual type of "secondary glaucoma" can develop. This condition, called rubeotic glaucoma, occurs in response to severe effects of diabetes on the circulation inside the eye. Rubeotic glaucoma can cause permanent damage to the eye within days of developing.

The biggest problem that diabetes causes in the eye is DIABETIC RETINOPATHY. This is a disease of the retina, the nerve layer that lines the inside of the back of the eye. The first signs of diabetic retinopathy come when the blood vessels inside the retina become "leaky". These blood vessels leak fluids that cause the retina to become swollen. As the retina swells, vision gets worse. This is called background diabetic retinopathy. Ophthalmologists can actually see this swelling when they examine the eye. When the swelling involves the center of vision, LASER surgery is performed to seal off the leaking areas. If the leakage is stopped, good vision remains. In more severe stages of the disease, the small blood vessels inside the eye begin to close down. In response to the lack of circulation, new blood vessels begin to grow. This is called proliferative diabetic retinopathy. These blood vessels are abnormal and cause more harm than good. They are prone to breaking and bleeding. If they do, sudden, severe loss of vision results. These blood vessels also lead to the formation of scar tissue that can cause retinal detachments. Fortunately, LASER surgery is also very effective in causing these abnormal blood vessels to shrink away and disappear.

Diabetic eye disease tends to worsen with time. The longer one has diabetes, the greater the risk of developing these conditions. Recent studies have shown that the risks of developing the complications of diabetes are related to how well the diabetic controls his or her blood sugar. The better the sugar is controlled, the less the likelihood of complications.

Ophthalmologists are fortunate in that we can see actual blood vessels inside the body. The changes that we see in the blood vessels of the eye of a diabetic are also occurring elsewhere in the body. If there is significant damage to the blood supply inside the eye, it is very likely that the same changes are occurring in the individual's heart, kidneys, brain and other major organs.

Aggressive, early treatment of diabetic eye disease has been shown to prevent loss of vision. All diabetics need to be examined by an ophthalmologist at least once each year so that these problems can be detected and treated before they cause permanent vision damage.

Copyright, 1997. Richard E. Gans, M. D.

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